Thursday, July 8, 2010

Explain how glucose can appear in urine in type 2 diabetes patients


Explain how glucose can appear in urine in type 2 diabetes patients?
Glucose a.absorption is uphill in kidney, gut etc. How can this occur? b.is freely filtered in the kidney and under “normal” conditions it is 100% reabsorbed (no glucose is found in urine). In type II diabetes mellitus, the absorption mechanism in the kidney is not affected. Glucose however, appears in urine. Explain how this can occur. I was thinking for A) that there is a cotransporter of some sort that allows it to go against a gradient but im stuck in part B. Could it be because glucose is not reabsorbed so therefore it is secreted out from the kidney into the urine?
Diabetes - 1 Answers
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You got in 1 try. Part B is correct Same way as it appeared in mine when I was a very young type 1 diabetic (diagnosed when I was 26 months old). When your blood sugar is too high for too long, it spills over into the urine I can smell when there is sugar in my urine, but I usually don't let my blood sugars remain high enough long enough to get into my urine now. I was diabetic even before Clinitest (for sugar in urine) and Acetest (for ketones in urine) came out in the early 1960's. I remember my mom doing Benedict's tests at night and boiling stuff every night.







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